Cannabis features more than 100 identified cannabinoids, but most of them are only present in very small amounts, less than 1%. The more abundant ones are THC, CBD, CBG, CBN, CBC and THCV. However, scientists have always been more focused on studying the composition and effects of THC and CBD, mainly because their levels in marijuana plants are higher.

THCV is a substance that is only recently starting to acquire relevance; after studies suggest that it can have beneficial medical effects. To this day, all the investigations are at a preliminary phase, therefore, conclusions aren’t clear yet. However, predictions are very encouraging as it seems its properties could help treat neurological and neurodegenerative disorders, as well as anxiety and inflammatory conditions, among others.

What is THCV?

Tetrahydrocannabivarin or THCV is one of the most present cannabinoids in marijuana plants, although the amounts are very small (<1%) in hemp plants and in the rest of cannabis strains.

thcv molecular composition

As it can be guessed by its name, its structure is very similar to THC, although its effects are more heterogeneous. The difference between them is based on the amount of carbon atoms present in its structure. THCV has two carbon atoms less than THC and such difference produces a different effect on the human body.

THCV levels are so low in most cannabis plants that it’s very hard to get useful concentrations of this substance, but modern methods are making it possible. For the moment, investigations seem to suggest that the potency of tetrahydrocannabivarin is 25% superior than THC, but that doesn’t imply higher psychoactive effects. As a matter of fact, there is a lot of controversy in that regard.

THCV effects

While some studies point out that THCV has nearly null psychotropic effects, others indicate that it depends on the dose. THCV relates to the endocannabinoid system of the human body in the same way that THC does, which is by using CB1 and CB2 receptors. These receptors are spread all over the body, through the central and peripheral nervous system and they are in charge of regulating a lot of functions in the body, such as blood pressure, temperature, respiratory frequency and sugar levels in the blood.

thcv and the endocannabinoid system

For this reason, there is a big chance that THCV has medical benefits, just like THC does. Even if it causes psychotropic secondary effects, as it works like a CB1 agonist receptor. This means that it can activate and modify its behavior. In the case of THCV, there is a big chance that, on low doses, it actually works like a CB1 antagonist receptor; therefore, not producing psychedelic effects. In large amounts, it can probably behave similarly to THC but its effects would be less long-lasting.

Regardless of how it works and the mental effects it produces, studies are very optimistic about the positive medical effects it can provide.

Health benefits

Although there have been no human trials backing up THCV’s benefits in people; animal trial results are very encouraging at proving the efficiency of this substance in certain conditions. 

  • Diabetes. THCV seems to regulate glucose levels in blood while reducing insulin resistance.
  • Obesity. Contrary to THC, tetrahydrocannabivarin is an excellent appetite suppressant.
  • Bone regeneration. This substance maybe intervenes in tissue regeneration and bone cell activity, as there are CB1 and CB2 receptors inside them.
  • Neurodegenerative conditions. THCV features antioxidant and neuroprotector properties that can delay and relieve the effects of Parkinson and Alzheimer; as well as other associated illnesses, such as epilepsy.
  • Anxiolytic. This component reduces anxiety levels in people with post-traumatic disorder (PTD). It also lowers stress, blood pressure and improves short-term memory.
  • Anti-inflammatory. This THCV characteristic alleviates any inflammatory alteration, such as Crohn’s disease, psoriasis and ulcerative colitis, among others.

 Lack of research makes it very difficult to use  THCV to confirm its benefits and to legalize the product.

Legality of THCV

THCV is a substance that has been unnoticed up until now. Thus it hasn’t been researched enough and it isn’t very well-known. These factors lead  to a lack of regulation over it.

Currently, this substance is not included in the Single Convention of Narcotic Drugs list; but due to its similarities with THC, it can be considered as equivalent. However, to this day, very few companies manufacture tetrahydrocannabivarin-based products. It is only available in tincture form. It is more expensive than other CBD or THC products because more raw material is needed to make the same volume of THCV.

African sativa

In most countries, its legality isn’t clear. Right now, it’s not even clear whether it’s a psychoactive substance or if it’s similar to CBD. 

Whichever case, the first step to give THCV visibility is to develop plants that are rich in this cannabinoid. The highest THCV concentrations are found in certain African sativas, but they are hard to find. Durban Poison (1%), Cherry Pie or Dough’s Varinn are the most popular ones. Kannabia Seed Company, wanting to get a step ahead in the field of plants with high THCV levels, is after creating a strain rich in this cannabinoid and it has called it just like its name, THCV. 

THCV by Kannabia Seed Company

This new Kannabia Seed Company is one of the first THCV-rich strains. It has been specially created for people that use cannabis for therapeutic purposes. THCV features a THCV : THC 1:1 ratio. In both cases, the percentage of these cannabinoids is 7%.

This feminized pure sativa features an indoor flowering period of 60-65 days. Outdoors, it will be ready by the end of September or the start of October. Besides its huge medical properties, THCV also has very interesting organoleptic properties, with intense aromas, citrus flavors and earthy touches. Its genetic code makes it ideal as a therapeutic strain. Its cannabinoids are capable of reducing the appetite, regulating blood sugar and strengthening the bone system. 

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Erik Collado

With more than 10 years of background in the cannabis sector, his experience and knowledge are the base of GB The Green Brand’s success

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